Methicillin-resistant Staphylococcus aureus (MRSA)-Biology

Methicillin-resistant Staphylococcus aureus (MRSA)-Biology

Order instructions:
• Title- This should be short and descriptive of your topic. Your goal is to inform the reader as to the objective or focus of your study in a brief statement. Vague or general titles will lose you points, and if your title is “The Plague”, or even worse, “Term Paper” you won’t earn any points, here. An example of an appropriate title would be “The Plague: Pathogenesis, Symptoms and Treatment”.
• General characteristics of the organism—What organism causes the disease? Is it a bacterium, virus, protozoan, etc…? If it is a bacterium is it Gram positive or Gram negative? Is it a DNA or RNA virus? How is the organism cultured in the lab and studied by microbiologists?
• Reservoirs—When the organism is not causing disease in a human host, where is it found in the environment? Is it in our food, water, soil or air? Is it found in an animal host? Do insects carry the organism? Or is it exclusive to humans, and not found anywhere else?
• Disease(s) caused by the organism—What disease does the organism cause? What is the impact of this disease on humanity? You may choose to include some statistics here, such as # of infections in the U.S. or worldwide each year, or the number of deaths caused by the organism annually. The CDC or WHO websites will be very helpful for this information.
• Transmission—How is your disease transmitted? It is airborne? Does it require an insect vector? Is it foodborne? Is it associated with close contact with animals? Does it require intimate contact between humans? Also, how does the disease enter the host? Does it come in through the skin, respiratory tract, digestive tract, or urogenital tract? Does it enter in some other manner?
• Symptoms of the disease—How does the disease present? What are the characteristic symptoms of infection, and are there other, less commonly observed symptoms? Are there long-term effects in infected individuals? How do the symptoms relate to how the organism enters and exits the body?
• Virulence Factors—Does your organism possess any important virulence factors that enable it to damage the host? What are they, and what do they do? For example, these virulence factors may impact some of the following processes:
o Survival of host defenses
o Attachment to and invasion of the host
o Damage to host by toxin production, stimulation of inflammation, cell destruction, etc.…
o Exit of host and spread to others
• Treatment—How are cases of the disease treated? Does the treatment differ for early or late stage infections? Are the available treatments effective? Are there any new treatments being developed?
• Epidemiology—Are there any risk factors that make a person more likely to contract the disease? Are there any populations that are more susceptible to this disease? Is there a seasonal patter to your disease, and if so, why? Are there sporadic, large-scale outbreaks in the population, or is your disease constantly infecting individuals at a low rate?

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