Below are the main points the writer should consider for creating the whole of the review based thesis including abstract, materials/methods, discussion, conclusion and references (many references at the end, 30-50 references at least) , and I need the sources of materials used at the end.
The main subject is : “RGD based targeted drug delivery systems in cancer Chemotherapy and cancer treatment”.
The following points must be referred and expanded while writing the thesis:
What is integrin and what are its subtypes? To what receptors it is related to and upond its activation what happens?
Where integrins are found?
functions of integrins?
To what ligands integrin binds?
Intracellular functions of Integrins?
Integrins and other RGD based receptors, what happens to them in case of cancer or metastasis, or related diseases?
How Integrin mediated signalling pathway works?
RGD applications in tumor therapy and chemotherapeutics?
Structure, activation and interactions related to integrins?
Overall, how RGD or its related mechanisms can be used in the treatment of cancer? What may be its potential uses in Pharmacy or medicine in the future?
