What are the mechanisms and the mediators of anaphylactic shock? Discuss the type of hypersensitivity reaction and the molecular mechanisms of anaphylactic shock.

1. What are the mechanisms and the mediators of anaphylactic shock? Discuss the type of hypersensitivity reaction and the molecular mechanisms of anaphylactic shock. What are some possible immediate and prophylactic treatment and how do they work?

2. What are differences between the primary and secondary immune response for antibody production? Why are booster shots given after the primary vaccine? Postulate on the long term effects of multiple vaccinations.

3. Explain how T cell education takes place in the thymus (be sure to include positive ands negative selection) and how self reactive T cells can escape to the periphery. Explain how the immune system then has at least two mechanisms to prevent recognition of self antigens in the periphery (be sure to cover the signal model and T regulatory cells).

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