What are the pathogenic mechanisms of Bordetella pertussis

1) What are the pathogenic mechanisms of Bordetella pertussis? What are its virulence factors?

2) Compare the difference between a cellular and an acellular vaccine.

3)What are the consequences of diminished vaccination? What impact does reduced vaccination have on herd immunity?

4)Sharing some of the research supported information and CDC statistics, why is there a resurgence of whooping cough?

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